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Sounds like a hardware issue, maybe bad, mismatched or improperly seated RAM (common in new machines), a hard drive going south, connections, cable, video RAM, etc.
Just a quick follow up, it does not do the problem in either Canon Raw or in Lightroom, if it was hardware wouldn't it do it there too? Also I have 4 hard drives, it does it on all of them.
It's impossible to troubleshoot someone else's machine remotely, especially without knowing what you have tried so far to track this down, what kind of maintenance routine you perform, even what kind of machine you have. "I have a mac dual 2.0 " tells me nothing, it could be a Dual Processor G4, G5 or even a Mac-Intel box or a laptop.
Nor do I know how much installed RAM you have, how much available memory you are allowing Photoshop to use in preferences, how much available disk space you have on your drives (both in GB and in %), whether you have your primary Photoshop scratch disk on a separate dedicated internal hard drive.
What exact versions of the software are you running? Photoshop 10.0.1? Bridge 18.104.22.168?
You're also not specifying what thumbnails you're looking at. In the Finder? Or in Bridge? If the latter, what version? Have you purged the Bridge cache for the offending folder(s) through the Tools menu in Bridge, one by one? DO NOT use the global Purge Cache command in Bridge preferences because it's broken (at least on the Mac) and your caches will NOT rebuild properly after using that global command.
Have you tried making a fresh new account on your Mac and logging in as a different user? (Not an existing user.) If so, does the problem persist or go away? This is a standard troubleshooting step.
But from your description of what you see, it does sound like an intermittent hardware issue. If the artifacts don't print (i.e. if they're only visible on the monitor but not on a printed image), suspect a faulty video card.
If it is an intermittent hardware issue, it doesn't matter that you haven't seen the issue on other applications. Photoshop is the ultimate RAM test, it can be brought down by bad RAM that even the software memory testing used by the engineers miss.
Have you tried trashing and rebuilding preferences? If you have Disk Warrior, have you run it?
It doesn't matter how many drives you have if it turns out to be a faulty video card, improperly seated RAM, RAM turned bad, mismatched RAM, bad cables, bad connections, etc.
What kind of batch action are you running? How?
I'm shooting in the dark here with next to no details from you.
Re routine maintenance:
I still advocate Repairing Permissions (with Apple's Disk Utility) before AND after any system update or upgrade, as well as before AND after installing any software that requires an installer that asks for your password.
I have seen software installations go sour because the installer did not find everything as and where it should be.
I have also seen software installations go bad because the installer did not clean up after itself properly and did not leave everything as and where it should be.
This is just my own personal opinion and practice based on my own observations. Others may disagree and that's OK. I can only base my routines and my advice to others on my own experience and conclusion. I don't pretend to know why others believe otherwise.
Repairing Permissions after the fact (i. e. not immediately before and after an install) may NOT help. Try it anyway, though.
Additionally, if your machine does not run 24/7 so that it runs the daily, weekly and monthly Cron Scripts in the middle of the night as intended by Apple, run Cocktail (shareware) as well.
Cron Scripts are maintenance routines designed by Apple to run on a daily, weekly and monthly basis in the middle of the night.
If you don't run them, you WILL run into trouble, sooner rather than later.
Here's an excerpt from the Apple tech doc http://docs.info.apple.com/article.html?artnum=107388
Mac OS X performs background maintenance tasks at certain times if the computer is not in sleep mode. If your computer is shut down or in sleep at the designated times, the maintenance does not occur. In that case, you may want or need to run these manually.
Mac OS X periodically runs background tasks that, in part, remove system files that are no longer needed. This includes purging older information from log files or deleting certain temporary items. These tasks do not run if the computer is shut down or in sleep mode. If the tasks do not run, it is possible that certain log files (such as system.log) may become very large.
Also, from: http://docs.info.apple.com/article.html?artnum=106978
The disk activity generated by find is a normal part of file system maintenance, used for tasks such as removing invisible temporary files that are used by the system. It is scheduled to occur early in the morning at 03:15 everyday, 04:30 on Saturdays, and 05:30 on the first day of each month.
NOTE: There have been comments to the effect that Apple "fixed" this in 10.4.2 and later versions of the OS, but I have not been able to verify this to my satisfaction. The reference in the 10.4.2 release notes are far from explicit on this subject.
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If you have DiskWarrior, run it regularly too.
Mac G5 Power PC
Dual 2 ghz
5.5 gb DDR SDRAM 85% to photoshop
Main drive applications only 160 gb/ 84 avail
2n internal drive 320 gb
Partitioned for 20 gb scratch drive
250 gb avail on b partition
firewire 4oo Maxtor 500gb archive drive 58 gb avail
firewire 800 OWC stripe raid 600 gb 473 avail
Photoshop 10 says update current
Finder thumbnails is the problem, sometimes the image opens fine, others file corrupt.
Bridge thumbs look fine.
Have not created new user.
Batch action processing Canon 5d raw images to tiffs or jpegs.
Machine runs 24/7 all Apple updates current
Do not have disc warrior.
Lance ... you do not state how raw files are transferred from your camera to your computer. That is, some users (not necessarily Canon) have expressed some problems when files are transferred direct -- camera=>computer -- as opposed to using an intermediate memory card reader.
I am using Compact flash card via usb reader.
Your 20GB Photoshop scratch drive partition is rather skimpy. Figure on as much as 35 to 50 times the size of your largest file or more.
I keep a dedicated, separate 160 GB internal drive as my primary Photoshop scratch disk drive.
However, I can't say that's the cause of the problems you are describing.
You still say nothing about Running Permissions before AND after every software update.
Have you tried the new account thing?
I tried the new account thing, seemed to work. I do not know how to run permissions. I am rather narrow focused in image processing and graphic design, (think kid in Deliverance with banjo) and have much to learn. I appreciate all input. Thank you. I am ordering Disc Warrior. I have no problem increasing scratch disc to 160gb.
If the new account works, an Archive and Install of the OS over your existing OS installation will give you a fresh system and preserve your settings. Should take less than 45 minutes.
To Repair Permissions, just launch Apple's Disk Utility, which is installed in your Applications folder / Utilities. It's pretty straight forward.