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First, how much space is left on your scratch disk? 10-15 minutes is a long time to be running before a crash...
Second, did you try deleting your preferences? Quit Illustrator. Hold down Command(apple), Control, Shift and restart Illustrator. It will ask if you want to delete your preferences. Say yes. See if it still crashes.
If it does, with no adobe apps running, delete your font caches. Both System and Application. There are a few ways to do this. I use FontExplorer to do it, but there are other smaller utilities/scripts to look at (search this forum for "font cache") After deleting the system font caches, you'll need to restart your computer.