Yes, we'd need to see it. This is not really possible. Flash
should render the content identically, regardless of the browser,
1) Check which version of the Flash Player you are targeting
in your application (under "Flex Compiler"). Hopefully, at least
2) Are the fonts looking different on different machines?
Embed them so they look the same everywhere.
3) Is it merely your app's position in the html page? This
could look different if the app is not taking up the entire screen.
It's position would then be entirely dependent on your HTML page's
code, and then subject to browser interpretation.