Adobe apps want to be on the C drive. If you get it to reside on a
different drive you will still find that a large chunk of code will
still be on the C drive. If you are running out of room the c drive it
is time to get a larger drive.
Do on command prompt a logical substitution to an existing folder on a real drive. For example:
Subst c: f:\DiskC
Assuming that F: is your existing system drive and "DiskC" is any existing directory. For this problem I created "diskC" directory only for that purpose.
Once executed a C: drive will appears in windows explorer that points exactly to f:\DiskC.
Start the install as usual. It could be longer to process but it will eventually succeed. Adobe installer don't really use the drive as no file is going to appear into f:\disqC directory. It seems this is an installer problem that query for disk C: existance. Everything is going to be installed to your system drive.