When trying to open any size PDF, Reader (8.1.1) takes an extremely long time to open the file. This is in a Terminal server enviornment so we do have certain features disabled such as the updater and kinkos.
The users are claiming anywhere from 40 seconds to several minutes. I'm unable to recreate since I do not use the environment like they do and it tends to be the more they open PDFs the slow it gets. I have seen a user try and open a 34k file and it took about 40 seconds to open and then trying to scroll is slow also.
I have found that if I reset the users profile it will allievate the problem for a day and then start all over again.