Simply put: Only CS3 is qualified for Vista. Everything else is a matter of "maybe". From my own experience I can say that AE7 runs on Vista, but it doesn't behave properly. Some panels will show odd behaviors and if you need to use it in a language that does not match the OS language, it creates a not-so-funny mess of English and whatever other language. Other users have constant problems with importing files or rendering to Quicktime, so it's not exactly a picnic in the park.