Here are the specs on a configure-to-order portable desktop replacement that looks like it might meet most of Harm's specifications. It is a Clevo D900F.
* 17" Wide Viewing Angles WUXGA Active Matrix Display 1920x 1200 with Super Clear Glossy surface
* Intel® Core™i7 Extreme processors support
* Intel® Xeon™ E5540, X5550, X5560, W5580 processors support
* NVIDIA® GeForce® GTX 280M 1GB graphics
* up to 12GB 1333MHz DDR3 SDRAM Memory Supported
* Support up to 3 Hard Disk Drives (Internally)
* Integrated Hardware SATA Raid 0,1, 5 Controller
* S-Video out jack for TV output & HDTV output
* 1 DVI Port, 1 VGA Port for external Monitors
* 4 Built-in Speakers
* 4 USB 2.0 Ports & 1 IEEE-1394 Ports
* Built-in 7-in-1 Card Reader
* Integrated 3MP Digital Video Camera
* Full Sized Keyboard with Numeric Keypad
* Intel High Definition Audio / 8 Channel external audio outputs supported
The base price for this 15 pound monster is $2565, outfitted with the base i7 920 CPU, three 320 GB 7200 rpm drives, a Blu-ray burner and 12 GB of RAM it goes for $4286.
But it is portable. One dealer is AVADirect. While not specified on this link another source has an eSATA Port also listed.