Are you trying to save your file locally or over a network? If a network, is your connection to the network good?
Is the directory/folder to which you're trying to save write-protected? Do you have sufficient rights to save the file at the given destination?
If you try saving the project to your desktop, does it work?
Found a workaround. I saved the file with a different name, erased the original and then changed the name back to the oginal. All dynamic links we're saved and are working fine. Thanks for the help :-)