After installing the latest version of Adobe Reader for Mac on Tiger 10.4, viewing any .pdf file has the effect of changing many of my single mouse clicks into double mouse clicks until reboot. It begins when I click on the page-down sidebar and the reader jumps ahead two pages. Next, randomly about 80% of my mouse clicks become double-clicks in any application until I reboot. I thought I had seen this problem in an earlier version but it seemed to resolve itself. With the latest reader, right after reading a .pdf file I have the double-click problem.
I've dragged everything I could find from Adobe into the trash bin and use "Preview" to view pdf file. No double-click problem.