A search for itss.dll will bring some interesting threads. It looks like you have already discovered the tech note http://www.adobe.com/go/rb_3188
Can your IT dept do the install and then change the user's rights back to normal afterwards? The threads between Peter Grainge and Dave Mozealous indicate some doubt about this, but it's worth a try.
Thanks for your reply, it is difficult to get the IT department to re-install, but if that is the only solution I can get back on their long list and wait it out.
If multiple user are using the same machine (not at the same time), will there be issues with the users who were not used to load the software?
Yes, RH is licenced to an individual person, not a single person. It will only work properly for the person whose logon was used to install it.
Maybe, a solution has already been found but since I faced a similar problem with RoboHelp 6.0 in Windows 7 (after upgrading from Windows XP), I thought I'll post a solution that worked for me for future reference. Following is the solution:
1. Go to Control Panel -> Programs.
2. Under Programs and Features, click Run programs made for previous versions of Windows.
3. In the Program Compatibility pop up window, click Advanced.
4. Follow the steps.
5. Save the settings after you ensure that the error message doesn't appear again.
Hope this helps somebody.