After a reboot of windows and 3rd attempt it seems to percist and encore seems to be broken. It used to work several weeks ago but something must have changed as it appears to be broken now.
Come to think of it I think I updated CS4 applications recently, maybe the update affected encore in a bad way? I guess I have to rely now on free alternatives to cut and edit my audio, very annoying and disappointing.
Install the latest pxhelp drivers and try to launch encore.
It may resolve this issue.
There are some hang issue on startup with CS4 and Windows 7.
You can install the pxhelp drivers from -