I think I see what is going on. It would appear that the mouse position for the Full Motion Recording (FMR) slide isn't capturing the ending location. Because of this, the mouse begins traveling from the ending point on the slide immediately before the click and drag.
You should report this to Adobe as a bug. (Link for doing that is in my signature)
As a workaround you will need to duplicate the slide that immediately follows the FMR slide. Remove all objects except the mouse then adjust the mouse position so it matches the position where it ended travel inside the FMR. Then time the slide super short. Perhaps .1 seconds.
Admittedly this will probably take a few attempts to get it right.
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Thank you for your quick response, I have filed a bug.
Unfortunately the workaround is not usable in my case as my videos have dozens of short FMR clips showing navigation. If I wanted to tinker I would use something free like Wink. This bug is a nasty one as all works nicely in version 4 and it pretty much breaks basic functionality in version 5.
There is a workaround to this issue:
1. Show the mouse in the FMR slide.
2. On this slide, drag the mouse to the end position of the drag-and-drop action (you will need to judge this by eye).
3. Having done this, Hide the mouse on the FMR slide again.
You should now find that the mouse starts from the correct position on the following slide.
Was this bug ever fixed? I am having the same problem but I cannot use the work around because my FMR is scrolling to an area of the window that is not visible until the end of the recording.