Have you installed the After Effects CS5 (10.0.1) update? If not, why not? If so, let us know how it's going for you.
Let us know what problems are fixed by this update for you. See this page for a long list of fixed items, added capabilities, and known issues.
Please continue to report bugs and use the crash reporter to let us know of problems that persist (or new ones).
> My #1 recurring crasher is "blitpipe disengaged"
Try disabling this preference: Hardware Accelerate Composition, Layer, And Footage Panels
Also, please submit a detailed bug report that says what you're doing when this crash occurs (on mouse up or mouse down? while dragging Exposure control? etc.).