Are you using Acrobat 8 or 9 ? Does it throw any error message on launching Acrobat, if yes then what is the error message that you are getting?
Also, kindly tell the OSX on which you are working
I'm using OS X version 10.6.4, Acrobate 9 Pro and there is no error messanges the icon will just bounce once in my dock then nothing. I've tried a restart and reinstalling the patch but same thing.