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There should be a setting in Reader preferences. Do you have Acrobat on your computer. If so you must make the change in Acrobat.
This is within Adobe Reader X. I don't have the other versions anymore.
Firstly during the installation of Reader X, there is an option of Customize Install. You can uncheck the Safari browser plugin from there. But this was possible before install. Now since you have installed in default mode (with above option checked during install) the method to disable plugin is as follows:
To disable the plugin-
1. Go to Library > Internet Plug-Ins
2. You will see AdobePDFViewer.plugin in the list of plugins
3. Create a new folder called Disabled Plug-Ins
4. Move the AdobePDFViewer plugin into the Disabled Plug-Ins folder
5. Restart Safari
In future if you want to re-enable this then you can put this plugin back to its original location or Reinstall Reader X (if you have permanently deleted the plug-in from your system). Reinstallation works as installing in repair mode.
AcrobatX/ReaderX uses MANAGED installation method on Mac(as compared to MANUAL installation method used in earlier versions). In case of manual installation method installation and repair was dependent on "Self heal" mechanism that required the admin privileges each time it was invoked. This raised a bit of concern so to remove this Adobe now uses Managed installation method and discontinued Self Heal mechanism.
You can check out this link for more information or if you want to track this discussion -
The official kb article confirms this as a 'Known Issue'. That's all I was asking about.
Then it's a known bug that Acrobat X shows the option in the Preferences, but doesn't allow users to actually do anything about it there. Nice one, Adobe. I'm becoming more fond of you everyday.