If you are pushing out using a GPO you can edit the .msi file with Adobe Customization Wizard, i believe you can chose the installation path through that, then save the settings as an .mst and add the .mst in the modifications tab when you first setup the GPO.
When I'm editing my msi with the Adobe Customization X, I can't select for it to remove previous version of Reader. Why is that?
Hmm, I'm not sure on that..
When i go to edit the .MSI with the Cusomization Wizard its already selected (and greyed out).
Try pushing the GPO to a test machine with a previous version of Adobe and see if it removes the previous adobe/upgrades it/nothing happens..
Well what has happened is that I have pushed an image out to a couple of thousand machines with Adobe Reader X in the wrong path. I need to correct it and was hoping that this would uninstall it and reinstall it in the correct path.