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I couldn't find the answer in previous discussions: I have Vista and have just tried to install the new Reader. I've turned off the McAfee firewall and antispam, used both Firefox and IE browsers, and grant permission to "Continue" when asked by Vista to download, but still get "Error 1321. The Installer has insufficient privileges to modify the file C:\Program Files\Adobe\Reader 10.0\Reader\Services\Services.cfg."