We are processing about 300 xml files (quite large) into PDF documents using Indesign templates in c#.
Is Indesign (the latest version) Desktop/Server multi-threaded? I tried threading with Desktop CS5 and it seems like it's only single-threaded. Is there anyway to make it multi-threaded or any performance tips?
No. InDesign is not multi-threaded -- with the exception file export.
InDesign Server can run multiple instances.