FYI, this discussion is copied from Acrobat Windows
I am using Acrobat Reader v10.0.1 in Windows7 (64-bit) with 12Gb of RAM and I encounter freezing of the application nearly every time I use it. This 'freezing' is observed as the image on the screen losing large portions of text or buttons with the applications faling to respond to any inputs. It seems to occur more on larger files but it is not limited to this. I also notice that I show multiple instances of the Acrobat.exe in task manager even though I have closed all but one document. In order to get around this problem, I have been killing all acrobat processes in task manager and then re-opening the documents I am reading. I can then work with those documents for awhile (awhile is a variable amount of time). I have uninstalled and re-installed version 10 and all of my video drivers are up to date. This is the only application that appears to freeze on this (new) computer.
ps. I have looked through the forums for a similar problem but none of them (I haven't gone through ALL of them yet) seem to match what I am seeing.
Over there http://forums.adobe.com/thread/850202?tstart=0 I suggested Microsoft's Virtual XP as a possible solution
Have you tried that to see if it works? (the link I provided was an example for one program... the Virtual XP mode is not just for that one program, it is for any 32bit program that does not want to work with Win7)
Also... you may right click the Reader icon and select a compatibility mode to see if that helps