Just checking here, is it a .txt file? If it is I can't think of anything at the moment, if it is could it be in some other format and carrying across some font information?
There are lots of reasons, generally related to character encoding. Please post a screenshot, so we know exactly what we're dealing with...
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Just because the TextEdit programs shows it as "plain text" doesn't mean that's how it is saved!
Notice how when you Save As in TextEdit you have the opportunity to specify UTF-8,UTF-16,Mac OS Roman, etc.?
And when you open in InDesign if you check Show Import Options you have the opportunity to do the same.
If there is a mismatch, than non-ASCII characters, such a curly-quote, will show just like that.
I believe your input text file is UTF-8, which is almost undoubtedly the correct choice. So Show Import Options when you place in InDesign and ensure you have Unicode UTF-8 selected as the Character Set.
Correct! That worked perfectly, thank you so much!