Firstly, I had the most recent version, but I'm back down to 10.-something because I tried re-installing after the crash problems.
Secondly, it has worked and nothing has changed... well, perhaps I updated to the newest Windows service pack, I can't be sure.
It's part of the CS5 master collection and all the other programs work just fine.
I'm afraid if you yourself don't know what's going on on your system, then we are not really able to help. NTDLL crashes 90% of the time are issues at the system level, which could be anything from permission issues with files to flakey graphics drivers, so look into that, especially since you installed your software on a different drive and not C:, which is not the safest thing to do with Adobe programs, unfortunately. Turn off security tools and virus scanenrs, update your graphics and otehr drivers, check fiel permissions aand user privileges. Also trash the AE prefs and monitor the spalsh screen when AE attempts to launch. That info alone could tell you everything you need to know to fix the problem...