I'm using CS4 and it's always worked fine on my old iMac. I've recently upgraded to a new iMac OSX Lion 10.7.1. I did a file transfer to move all of my data, and CS4 is installed on my new machine. Everything is opening except Indesign. It crashed immediately. I tried trashing the preferences, but that didn't help. Has anyone had this problem, and have any suggestions.
Using a file transfer is probably the cause of your problem. When you change computers it's recommended that you deactivate and uninstall on the first computer and use the Creative Suite installer to install on the second.
Try uninstalling and reinstalling.