After I click/use anything from my custom Configurator panel in PS5, I can not use any of the normal keyboard shortcuts (like holding down the space bar to move the image on screen). It makes my mac sound the "error beep." It's driving me nuts. I notice that when I press the spacebar after running something, it highlights one of my Configurator buttons (like my spacebar is triggering one of my panel items).
The only way to get keyboard shortcuts to work is to click a layer in the layers panel.
I had the same problem, the focus stays with the Flash panel so you would have to click on a Photoshop component or hit ESC.
I have just added BridgeTalk.bringToFront("photoshop"); in all my scripts invoked by a Flash panel, this should probably work in Configurator as well.