Red slice guides visible when clicking on a page the first time

This has been around for a few versions now and it's always bugged me but clearly not enough to do anything about it.... When you click on a page that has slices on it after opening the file, you always see the red slice guides even though the Web layer is turned off. To get rid of these guides, you have to turn the Web layer on then off again. Crazy. I've searched a fair bit but not seen anything about this.

Can anyone help?

Cheers

Paul