Sounds like your computer is short of resources. What OS, version of Reader, RAM, and free hard drive space.? Before reporting back try to empty your temp folders and see if it makes a difference.
I doubt its system resources, its a desktop purchased last year. I can get the system specs, but it doesnt seem like that could be the culprit. I did however empty the temp internet files but i wasnt going to waste 110+ pages to see if that fixed it. I wonder if there is something to do with how Adobe operates, if it is a single instance only program or if because its Pro there are some other aspects that would limit opening a document while sending one to the printer. Keep in mind its taking roughly 10 minutes to send the document to the printer. Once the print is fully sent the files can be opened fine, also the computer isnt locking up entirely its only opening other PDF files that gets blocked. The Lotus Notes we use for mail here still functions properly as well as the web browser, just cant open pdfs.... Its strange.
I am still having this really strange problem, anyone have any suggestions? **NOTE** I did try using a different comp to rule out hardware problems, the same thing happens, while printing when you try to open a document nothing happens at all until printing finishes then all of a sudden all the files you tried to open while printing open up all at once. Is there some setting or restriction i dont know about that is forcing me into this? I am printing 100+ pages of paper size Arch D (36X42) so having to wait to do any work on pfd's while this massive print job is going on really sucks. Also the printers are network printers to the information being sent to the printer is off the computer really quickly, so i dont think it has something to do with being lagged out or anything.
Really any help at all would be great!