Can you enable LCDS logging and see if you are seeing any errors? What client (Flex, JS, iOS, Java) are you using? In general, you can bound the timeout on request. Look at the documentation for client (Flex, JS, iOS, Java) are you using, for how to do it.
Thanks for your suggestion. I am using flex as client but problem is that same configuration is working fine with some applications. Can you tell what may affect response time ,please ? For your reference, if I use blazeDS, response time if fine.