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I think, you should spend time to learn Muse, before starting serious projects. A good starting point is here: https://helpx.adobe.com/support/muse.html
Web design and print design are completely different. In print design pages are static, in web design, every element interferes with each other, and this makes things complex.
My suggestion in this case: Start with a fixed width site and fixed width breakpoints. In this case layouting will be quite similar as you are used to in print design.
The only issue, which I can identify from your post is „I can’t select anything on any page except the master page."
You may have to learn, that Muse is in some aspects similar to InDesign, but not identical at all. Different design intentions need different tools and approaches. One difference is, that master page elements in Muse can’t be activated on layout pages.
Unfortunately you don’t explain the other issues, you are facing, thus making it impossible to help.
The simplest way to get help is, to explain the issues, exactly, create a small sample .muse file demonstrating the problem, and share the .muse file with us, using these instructions: https://forums.adobe.com/docs/DOC-8652
Thank you so much Günter,
Now I get it - I don't recall reading that anywhere. The other problems I am encountering are listed in this posting: Re: Problems in Muse with items scrolling when they need to be fixed
and I have had some help but haven't explored all options yet. I shall go through everything though.